Compare graphics card gaming performance. I can only assume that this has to do with having two different brand monitors as they might have different power requirements? I honestly don't have anything more than guesses. GPU Comparison Specs & Benchmarks AMD FirePro W4100 vs ATI Radeon HD 5870. So I know that the card is capable of making it work, but why does it not always work? Literally any responses would be wonderful. I can occasionally get it to work, but only if I redownload the amd firepro software, restart the computer, and unplug and replug the monitors (Not always in that order). If I extend to the second monitor it works, I'll see this:Īnd when I click the other ones to extend, I see this. On mine, if I restart my computer the 3 other screen will go black and windows will recognize them but not display on them. I will say that mine is the only one that has different monitors (2 Acer, 2 Asus, but they are the same size and resolution). We all have the same HDMI to mini DP cables. The AMD FirePro W4100 professional graphics card represents a completely new class of product one that provides you with great graphics performance and display. The AMD firepro W4100 works perfectly on every other computer on a 4 monitor set up. We all have the same computer and the majority of us have 4 monitor setups. I have a Windows 10 computer in the office I work.